Search results for "Tumour stage"
showing 5 items of 5 documents
Art und Prognose des lokoregionären Rezidivs beim Rektumkarzinom: Eine Nachsorgestudie
2008
The recurrence rate after 438 curative operations for rectal carcinoma was 44.1% (193 cases). It was independent of age and sex, but correlated closely with tumour stage. Tumours in an early stage recurred rarely and late. The success of a second operation was influenced by the type of local-regional recurrence. Only three of 34 presacral recurrences were again treated surgically with cure as the aim, compared with seven of 17 anastomosis recurrences, five of eight perineal recurrences, four of six recurrences after local dissection, and all colostomy recurrences, vaginal recurrences and metachronic second tumours. The further course demonstrated that about three quarters of patients who ha…
Treatment with metformin is associated with a prolonged survival in patients with hepatocellular carcinoma
2019
BACKGROUND Hepatocellular carcinoma (HCC) is one of the most lethal cancers. Nutrition- and life style-associated risk factors are increasingly prevalent. Metformin, the mainstay of type 2 diabetes mellitus (T2DM)-treatment, reduces the risk of hepatocarcinogenesis. However, its influence on the prognosis of patients with HCC has not been investigated on a large scale, yet. METHODS Five thousand and ninety-three patients treated for HCC between 2000 and 2016 at three referral centres were included in this retrospective multicentre study. The aim of this study was to assess whether treatment with metformin for T2DM is associated with a prolonged overall survival (OS) in patients diagnosed wi…
Prognostic scores for hepatocellular carcinoma: none is the winner
2009
Cancer classification and indication of treatment are critical steps in the management of patients with hepatocellular carcinoma (HCC). The prediction of outcome is relevant to provide adequate information to patients and relatives, both at the time of treatment selection and after the application of therapy. Tumour staging describes the extent of an individual's tumour burden in the original primary organ and spread throughout the body, and other cofactors such as age or histological grade are only seldom considered. This is common to all malignancies and diseases. However, whereas for most neoplasms prognosis and treatment are largely dictated by tumour stage at the time of diagnosis, the…
Breast cancer screening : socioeconomic factors influencing the participation and screening round adequacy
2013
Mammography screening allowed breast tumors detection in early stage while treatments are less aggressive. Despite the fact that organized mammography screening has been free of charge for the target population since 2004 in France, the participation rate to the programme remains low.The aim of the studies was to investigate individual and area-level socioeconomic factors explaining low breast cancer screening attendance, individual factors influencing mammography screening round adequacy and to assess the evidence of screening round adequacy in the discovery of breast tumors.The results showed that women living in most deprived areas or rural areas, those covered by self-employed insurance…
Prognostic markers in low-grade papillary urothelial neoplasms of the urinary bladder: an update
2009
Abstract Papillary urothelial neoplasms of the urinary bladder comprise a heterogeneous spectrum of ‘continuous' lesions in which the assessment of an accurate histological grade and tumour stage is mandatory for the clinical management of patients. The 1998 World Health Organization/International Society of Urologic Pathologists (WHO/ISUP) consensus classification and the 1999 WHO classification proposed new malignancy grading schemes, mainly based on morphometric studies for the replacement of the 1973 WHO grading system. In accordance with these novel grading systems, two major categories of papillary urothelial neoplasms were distinguished: low-grade and high-grade papillary urothelial …